Anti-Human CD80 Rabbit Recombinant Antibody, PBS Only

CD80 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98384-1-PBS

产品说明书

CloneNo. 242913B11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

Activation B7 1 antigen, Activation B7-1 antigen, B7, B7 1, B7-1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

98384-1-PBS targets CD80 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD80 molecule
别名 Activation B7 1 antigen, Activation B7-1 antigen, B7, B7 1, B7-1
计算分子量33 kDa
GenBank蛋白编号NM_005191
基因名称 CD80
Gene ID (NCBI) 941
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP33681
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215)

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