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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of BALB/c mouse splenocytes using 98161-1-RR (same clone as 98161-1-PBS)

    FC experiment of BALB/c mouse splenocytes using 98161-1-RR (same clone as 98161-1-PBS)

    1x10^6 BALB/c mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD6 Rabbit Recombinant Antibody (98161-1-RR, Clone:241471F3) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3. Cells were not fixed. This data was developed using the same antibody clone with 98161-1-PBS in a different storage buffer formulation.

  • FC experiment of BALB/c mouse splenocytes using 98161-1-RR (same clone as 98161-1-PBS)

    FC experiment of BALB/c mouse splenocytes using 98161-1-RR (same clone as 98161-1-PBS)

    1x10^6 BALB/c mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD6 Rabbit Recombinant Antibody (98161-1-RR, Clone:241471F3) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98161-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98161-1-RR

    Affinity and Kinetic Characterization of 98161-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98161-1-RR against Mouse CD6 were performed. The affinity constant is 0.658 nM.

Anti-Mouse CD6 Rabbit Recombinant Antibody, PBS Only

CD6 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98161-1-PBS

产品说明书

CloneNo. 241471F3

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

241471F3, T-cell differentiation antigen CD6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98161-1-PBS targets CD6 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 CD6 fusion protein Eg1401 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD6 antigen
别名 241471F3, T-cell differentiation antigen CD6
计算分子量72kDa
GenBank蛋白编号NM_009852.3
基因名称 Cd6
Gene ID (NCBI) 12511
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ61003-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD6 is a type I transmembrane glycoprotein that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.