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验证数据展示

  • FC experiment of human blood using 98493-3-RR (same clone as 98493-3-PBS)

    FC experiment of human blood using 98493-3-RR (same clone as 98493-3-PBS)

    1x10^6 human blood cells were surface stained with 0.25 ug Anti-Human CD55 Rabbit RecAb (98493-3-RR, Clone: 250682C11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98493-3-PBS in a different storage buffer formulation.

  • FC experiment of human blood using 98493-3-RR (same clone as 98493-3-PBS)

    FC experiment of human blood using 98493-3-RR (same clone as 98493-3-PBS)

    1x10^6 human blood cells were surface stained with 0.25 ug Anti-Human CD55 Rabbit RecAb (98493-3-RR, Clone:250682C11) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98493-3-PBS in a different storage buffer formulation.

Anti-Human CD55 Rabbit Recombinant Antibody, PBS Only

CD55 Uni-rAb® Recombinant Antibody for FC
Cat No. 98493-3-PBS

产品说明书

CloneNo. 250682C11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

Complement decay-accelerating factor, CR, CROM, DAF, TC

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98493-3-PBS targets CD55 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg4246

Product name: Recombinant Human CD55 protein (rFc Tag)(HPLC verified)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 35-353 aa of BC001288

Sequence: DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
别名 Complement decay-accelerating factor, CR, CROM, DAF, TC
计算分子量 41 kDa
GenBank蛋白编号BC001288
基因名称 CD55
Gene ID (NCBI) 1604
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP08174
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044).

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