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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD44 Mouse IgG2a Recombinant Antibody (65608-1-MR, Clone: F10-44-2) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65608-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD44 Mouse IgG2a Recombinant Antibody (65608-1-MR, Clone: F10-44-2) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65608-1-PBS in a different storage buffer formulation.

Anti-Human CD44 (F10-44-2) Mouse IgG2a Recombinant Antibody, PBS Only

CD44 Recombinant Antibody for FC
Cat No. 65608-1-PBS

产品说明书

CloneNo. F10-44-2

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

Epican, ECMR-III, ECMR III, CSPG8, CDW44

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CD44 Ready-To-Use IHC Kit. CD44 primary antibody included.

产品信息

65608-1-PBS targets CD44 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 N/A 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 CD44 molecule (Indian blood group)
别名 Epican, ECMR-III, ECMR III, CSPG8, CDW44
计算分子量 742 aa, 82 kDa
GenBank蛋白编号BC004372
基因名称 CD44
Gene ID (NCBI) 960
ENSEMBL Gene IDENSG00000026508
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.