Mouse CD40L/CD154 Recombinant antibody, PBS Only

CD40L/CD154 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 83884-3-PBS

产品说明书

CloneNo. 240743F5

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, ELISA

CD154, Cd40l, 240743F5, CD40 ligand, Cd40lg

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

83884-3-PBS targets CD40L/CD154 in WB, ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, ELISA Application Description
经测试反应性 mouse
免疫原 CD40L/CD154 fusion protein Eg0990 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD40 ligand
别名 CD154, Cd40l, 240743F5, CD40 ligand, Cd40lg
计算分子量29 kDa
观测分子量32 kDa
GenBank蛋白编号NM_011616.2
基因名称 CD154
Gene ID (NCBI) 21947
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP27548
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The CD40 ligand (CD40L, TRAP, CD154), a member of the TNF superfamily of ligands, is expressed as either a 33 kDa transmembrane homologue or an 18 kDa soluble form (sCD154). CD40L is primarily expressed on activated CD4+ T cells and a small proportion of CD8+ T cells and platelets. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. Recent studies have suggested that CD40/CD40L interactions regulate oxidative stress and affect various signaling pathways in both the immunological and the cardiovascular systems. The CD40/CD40L system is also involved in tumorigenesis.

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