CoraLite® Plus 647 Anti-Mouse CD38 (90)
CD38 Monoclonal Antibody for FC, IF/ICC
Host / Isotype
Rat / IgG2a, kappa
Reactivity
Mouse
Applications
FC, IF/ICC
Conjugate
CoraLite® Plus 647 Fluorescent Dye
CloneNo.
90
验证数据展示
经过测试的应用
| Positive IF detected in | mouse splenocytes |
| Positive FC detected in | mouse splenocytes |
For other applications, we recommend the unconjugated version of this antibody, 65059-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:200-1:800 |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL647-65059 targets CD38 in IF, FC applications and shows reactivity with Mouse samples.
| Tested Applications | FC, IF/ICC |
| Tested Reactivity | Mouse |
| Immunogen | Mouse bone marrow pre-B cells 种属同源性预测 |
| Host / Isotype | Rat / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | CD38 antigen |
| Synonyms | Cd38, CD38 antigen, Cd38 rs1 |
| GenBank Accession Number | BC046312 |
| Gene Symbol | Cd38 |
| Gene ID (NCBI) | 12494 |
| RRID | AB_2883660 |
| Conjugate | CoraLite® Plus 647 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
| Form | Liquid |
| Purification Method | Affinity purification |
| UNIPROT ID | P56528 |
| Storage Buffer | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 647 CD38 antibody CL647-65059 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
