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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • FC experiment of human PBMCs using 65622-1-MR (same clone as 65622-1-PBS)

    FC experiment of human PBMCs using 65622-1-MR (same clone as 65622-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD35 (E11) Mouse IgG2a Recombinant Antibody (65622-1-MR, Clone: E11) or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4) and PE-conjugated Goat Anti-Mouse IgG. Cells were then stained with APC Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 65622-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65622-1-MR (same clone as 65622-1-PBS)

    FC experiment of human PBMCs using 65622-1-MR (same clone as 65622-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD35 (E11) Mouse IgG2a Recombinant Antibody (65622-1-MR, Clone: E11) (red) or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4) (blue) and PE-conjugated Goat Anti-Mouse IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 65622-1-PBS in a different storage buffer formulation.

    {{ptg:ProductFeaturesInfo}}

Anti-Human CD35 (E11) Mouse IgG2a Recombinant Antibody, PBS Only

CD35 Uni-rAb® Recombinant Antibody for FC
Cat No. 65622-1-PBS

产品说明书

CloneNo. E11

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

KN, E11, CR1, Complement receptor type 1, C3BR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy CR1/CD35 Ready-To-Use IHC Kit. CR1/CD35 primary antibody included.

产品信息

65622-1-PBS targets CD35 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

fusion protein

种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 complement component (3b/4b) receptor 1 (Knops blood group)
别名 KN, E11, CR1, Complement receptor type 1, C3BR
计算分子量 224 kDa
GenBank蛋白编号NM_000573
基因名称 CR1
Gene ID (NCBI) 1378
ENSEMBL Gene IDENSG00000203710
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP17927
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes.