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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
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Compatible Species
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Conjugate
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验证数据展示

  • FC experiment of mouse splenocytes using 98258-1-RR (same clone as 98258-1-PBS)

    FC experiment of mouse splenocytes using 98258-1-RR (same clone as 98258-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.15 ug Anti-Mouse CD31 Rabbit Recombinant Antibody (98258-1-RR, Clone: 242041B5) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse CD45R (B220) (RA3-6B2) (APC-65139, Clone: RA3-6B2). Cells were not fixed. This data was developed using the same antibody clone with 98258-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98258-1-RR (same clone as 98258-1-PBS)

    FC experiment of mouse splenocytes using 98258-1-RR (same clone as 98258-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.15 ug Anti-Mouse CD31 Rabbit Recombinant Antibody (98258-1-RR, Clone:242041B5) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98258-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98258-1-RR

    Affinity and Kinetic Characterization of 98258-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98258-1-RR against Mouse CD31 were performed. The affinity constant is 0.547 nM.

Anti-Mouse CD31 Rabbit Recombinant Antibody, PBS Only

CD31 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98258-1-PBS

产品说明书

CloneNo. 242041B5

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

PECAM-1, Pecam1, PECAM 1, Pecam, 242041B5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98258-1-PBS targets CD31 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 platelet/endothelial cell adhesion molecule 1
别名 PECAM-1, Pecam1, PECAM 1, Pecam, 242041B5
计算分子量81 kDa
GenBank蛋白编号NM_001305157.1
基因名称 CD31
Gene ID (NCBI) 18613
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ08481-1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD31, also known as PECAM1 (Platelet endothelial cell adhesion molecule), is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. It is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, CD31 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).