验证数据展示
经过测试的应用
Positive FC detected in | Anti-CD3/CD28 treated mouse splenocytes |
推荐稀释比
应用 | 推荐稀释比 |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
98209-1-RR targets CD30/TNFRSF8 in FC applications and shows reactivity with mouse samples.
经测试应用 | FC Application Description |
经测试反应性 | mouse |
免疫原 | Recombinant protein 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | tumor necrosis factor receptor superfamily, member 8 |
别名 | Tumor necrosis factor receptor superfamily member 8, Tnfrsf8, Lymphocyte activation antigen CD30, CD30L receptor, CD30 |
计算分子量 | 53kDa |
GenBank蛋白编号 | NM_009401.2 |
基因名称 | Tnfrsf8 |
Gene ID (NCBI) | 21941 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q60846 |
储存缓冲液 | PBS with 0.09% sodium azide , pH 7.3 |
储存条件 | Store at 2 - 8°C. Stable for one year after shipment. |
背景介绍
CD30, also known as TNFRSF8 or Ki-1, is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is composed of an extracellular domain with six cysteine-rich repeats, a transmembrane segment, and an intracellular domain (PMID: 1310894). CD30 is expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (PMID: 9826579; 28885612). The CD30 ligand (CD30L or CD153) is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily (PMID: 8701986). Signal transduction of CD30/CD30L utilizes signal transducers, TNFR-associated factors (TRAF1, 2, 3 and 5) (PMID: 9826579).
实验方案
Product Specific Protocols | |
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FC protocol for CD30/TNFRSF8 antibody 98209-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |