Anti-Mouse CD30/TNFRSF8 Rabbit Recombinant Antibody

CD30/TNFRSF8 Recombinant Antibody for FC
Cat No. 98209-1-RR

产品说明书

CloneNo. 241710B4

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

Tumor necrosis factor receptor superfamily member 8, Tnfrsf8, Lymphocyte activation antigen CD30, CD30L receptor, CD30

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive FC detected inAnti-CD3/CD28 treated mouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98209-1-RR targets CD30/TNFRSF8 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 8
别名 Tumor necrosis factor receptor superfamily member 8, Tnfrsf8, Lymphocyte activation antigen CD30, CD30L receptor, CD30
计算分子量53kDa
GenBank蛋白编号NM_009401.2
基因名称 Tnfrsf8
Gene ID (NCBI) 21941
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ60846
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

CD30, also known as TNFRSF8 or Ki-1, is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is composed of an extracellular domain with six cysteine-rich repeats, a transmembrane segment, and an intracellular domain (PMID: 1310894). CD30 is expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (PMID: 9826579; 28885612). The CD30 ligand (CD30L or CD153) is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily (PMID: 8701986). Signal transduction of CD30/CD30L utilizes signal transducers, TNFR-associated factors (TRAF1, 2, 3 and 5) (PMID: 9826579).

实验方案

Product Specific Protocols
FC protocol for CD30/TNFRSF8 antibody 98209-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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