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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of mouse splenocytes using 98195-1-RR (same clone as 98195-1-PBS)

    FC experiment of mouse splenocytes using 98195-1-RR (same clone as 98195-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD28 Rabbit Recombinant Antibody (98195-1-RR, Clone: 241707H6) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse CD3. Cells were not fixed. This data was developed using the same antibody clone with 98195-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98195-1-RR (same clone as 98195-1-PBS)

    FC experiment of mouse splenocytes using 98195-1-RR (same clone as 98195-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD28 Rabbit Recombinant Antibody (98195-1-RR, Clone:241707H6) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98195-1-PBS in a different storage buffer formulation.

Anti-Mouse CD28 Rabbit Recombinant Antibody, PBS Only

CD28 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98195-1-PBS

产品说明书

CloneNo. 241707H6

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

T-cell-specific surface glycoprotein CD28, CD28 antigen, 241707H6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98195-1-PBS targets CD28 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 FusionProtein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD28 antigen
别名 T-cell-specific surface glycoprotein CD28, CD28 antigen, 241707H6
计算分子量25 kDa
GenBank蛋白编号NM_007642.4
基因名称 Cd28
Gene ID (NCBI) 12487
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP31041
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD28 (T-cell-specific surface glycoprotein CD28), also known as T44 and Tp44, is a 44 kD disulfide-linked homodimeric type I glycoprotein (PMID: 2162180). It is a member of the immunoglobulin superfamily and is expressed on most T lineage cells, NK cell subsets, and plasma cells (PMID: 2162180, 8386518). CD28 may affect in vivo immune responses by functioning both as a cell adhesion molecule linking B and T lymphocytes and as the surface component of a novel signal transduction pathway (PMID: 2162180, 3021470). CD28 binds both CD80 and CD86 with a highly conserved motif MYPPY in the CDR3-like loop (PMID: 15696168, 7964482). CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death (PMID: 1348520).