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验证数据展示

  • WB analysis of human peripheral blood platelets using 67653-1-Ig (same clone as 67653-1-PBS)

    WB analysis of human peripheral blood platelets using 67653-1-Ig (same clone as 67653-1-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67653-1-Ig (CD226 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67653-1-PBS in a different storage buffer formulation.

CD226 Monoclonal antibody, PBS Only

CD226 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67653-1-PBS

产品说明书

CloneNo. 7G7A4

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, Indirect ELISA

别名

CD226, CD226 antigen, CD226 molecule, DNAM 1, DNAM1, DNAX accessory molecule 1, PTA1, TLiSA1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67653-1-PBS targets CD226 in WB, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human
免疫原 CD226 fusion protein Ag12403 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 CD226 molecule
别名 CD226, CD226 antigen, CD226 molecule, DNAM 1, DNAM1, DNAX accessory molecule 1, PTA1, TLiSA1
计算分子量 336 aa, 39 kDa
观测分子量 65 kDa
GenBank蛋白编号BC074787
基因名称 CD226
Gene ID (NCBI) 10666
ENSEMBL Gene IDENSG00000150637
RRIDAB_2882852
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ15762
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).