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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 65591-1-MR (same clone as 65591-1-PBS)

    FC experiment of human PBMCs using 65591-1-MR (same clone as 65591-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD21 Mouse IgG2a Recombinant Antibody (65591-1-MR, Clone: BU32) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD19. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65591-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65591-1-MR (same clone as 65591-1-PBS)

    FC experiment of human PBMCs using 65591-1-MR (same clone as 65591-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD21 Mouse IgG2a Recombinant Antibody (65591-1-MR, Clone: BU32) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65591-1-PBS in a different storage buffer formulation.

Anti-Human CD21 (BU32) Mouse IgG2a Recombinant Antibody, PBS Only

CD21 Recombinant Antibody for FC
Cat No. 65591-1-PBS

产品说明书

CloneNo. BU32

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

EBV receptor, CR2, Complement receptor type 2, Complement C3d receptor, C3DR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

65591-1-PBS targets CD21 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 N/A 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 complement component (3d/Epstein Barr virus) receptor 2
别名 EBV receptor, CR2, Complement receptor type 2, Complement C3d receptor, C3DR
计算分子量 1092 aa, 119 kDa
GenBank蛋白编号BC136394
基因名称 CD21
Gene ID (NCBI) 1380
ENSEMBL Gene IDENSG00000117322
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP20023
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD21, also known as complement receptor type 2 (CR2), complement C3d receptor, and Epstein-Barr virus receptor, is a transmembrane protein that contains a small cytoplasmic domain, a transmembrane region and an extracellular domain consisting of 15 tandem short consensus repeat sequences (PMID: 6230668; 2551147). It is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells (PMID: 26119182). CD21 binds complement fragments C3d, C3dg and iC3b and acts as a receptor for the Epstein-Barr virus (PMID: 7753047). On B cells, together with CD19 and CD81, CD21 forms a complex that functions as a co-receptor to the BCR (PMID: 7542009). It is involved in B cells activation and functions.