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验证数据展示

  • IF Staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    IF Staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human skin cancer tissue using CD207/Langerin antibody (67788-1-Ig, Clone: 1H3A1 ) at dilution of 1:20000 and CoraLite®594-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-3). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

CD207/Langerin Monoclonal antibody, PBS Only

CD207/Langerin Monoclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 67788-1-PBS

产品说明书

CloneNo. 1H3A1

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IHC, IF-P, Indirect ELISA

别名

CD207, Langerin, 1H3A1, CD207 molecule, langerin, CLEC4K

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

67788-1-PBS targets CD207/Langerin in IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag2479

Product name: Recombinant human CD207 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-328 aa of BC022278

Sequence: MTVEKEAPDAHFTVDKQNISLWPREPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSARFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 CD207 molecule, langerin
别名 CD207, Langerin, 1H3A1, CD207 molecule, langerin, CLEC4K
计算分子量 328 aa, 37 kDa
GenBank蛋白编号BC022278
基因名称 CD207
Gene ID (NCBI) 50489
RRIDAB_2918552
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ9UJ71
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD207 protein (also known as langerin protein) is encoded by the CD207 gene and is a type of C-type lectin receptor that is specifically expressed on the surface of LCs. It is one of the specific immunohistochemical markers of LCs (PMID: 37383183, PMID: 28109175). CD207 plays an important role in a series of non-classical antigen processing processes, such as forming Birbeck granules and processing and transporting them to local lymphoid tissue, and inducing LC maturation (PMID: 32326440).

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