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  • IF Staining of human skin cancer using 67788-1-Ig

    IF Staining of human skin cancer using 67788-1-Ig

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human skin cancer tissue using CD207/Langerin antibody (67788-1-Ig, Clone: 1H3A1 ) at dilution of 1:20000 and CoraLite®594-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-3). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human skin cancer using 67788-1-Ig

    IHC staining of human skin cancer using 67788-1-Ig

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human skin cancer using 67788-1-Ig

    IHC staining of human skin cancer using 67788-1-Ig

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human skin cancer using 67788-1-Ig

    IHC staining of human skin cancer using 67788-1-Ig

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CD207/Langerin Monoclonal antibody

CD207/Langerin Monoclonal Antibody for IHC, IF-P, ELISA
Cat No. 67788-1-Ig

产品说明书

CloneNo. 1H3A1
引用文献(3)

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IHC, IF-P, ELISA and More (2)

别名

CD207, Langerin, 1H3A1, CD207 molecule, langerin, CLEC4K

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive IHC detected inhuman skin cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF-P detected inhuman skin cancer tissue

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:5000-1:20000
Immunofluorescence (IF)-PIF-P : 1:10000-1:40000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

67788-1-Ig targets CD207/Langerin in WB, IHC, IF-P, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF-P, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human
文献引用反应性human
免疫原

CatNo: Ag2479

Product name: Recombinant human CD207 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-328 aa of BC022278

Sequence: MTVEKEAPDAHFTVDKQNISLWPREPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSARFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 CD207 molecule, langerin
别名 CD207, Langerin, 1H3A1, CD207 molecule, langerin, CLEC4K
计算分子量 328 aa, 37 kDa
GenBank蛋白编号BC022278
基因名称 CD207
Gene ID (NCBI) 50489
RRIDAB_2918552
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ9UJ71
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CD207 protein (also known as langerin protein) is encoded by the CD207 gene and is a type of C-type lectin receptor that is specifically expressed on the surface of LCs. It is one of the specific immunohistochemical markers of LCs (PMID: 37383183, PMID: 28109175). CD207 plays an important role in a series of non-classical antigen processing processes, such as forming Birbeck granules and processing and transporting them to local lymphoid tissue, and inducing LC maturation (PMID: 32326440).

实验方案

Product Specific Protocols
IF protocol for CD207/Langerin antibody 67788-1-IgDownload protocol
IHC protocol for CD207/Langerin antibody 67788-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Elife

Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation.

Authors - Toshiyuki Oda
View Article
humanIF

Bioeng Transl Med

Assessing the impact of airborne particulate pollution on human skin utilizing a novel human skin equivalent containing MUTZ-3-derived Langerhans cells

Authors - Amy Simpson
View Article
humanIHC

Naunyn Schmiedebergs Arch Pharmacol

Biocompatible hydrogel eradicates pregnancy-associated genital warts.

Authors - Zhaohui Yang
View Article
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