验证数据展示
产品信息
65598-1-PBS targets CD178 (Fas ligand) in FC applications and shows reactivity with human samples.
经测试应用 | FC Application Description |
经测试反应性 | human |
免疫原 | L5178Y mouse T lymphoma cells expressing recombinant human FasL 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | Fas ligand (TNF superfamily, member 6) |
别名 | CD178, Fas ligand, FASLG, CD95-L, CD95L |
计算分子量 | 281 aa, 31 kDa |
GenBank蛋白编号 | BC017502 |
基因名称 | Fas Ligand |
Gene ID (NCBI) | 356 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.