Anti-Mouse CD16/CD32 (93), PBS Only

CD16/CD32 Monoclonal Antibody for FC
Cat No. 65057-1-PBS

产品说明书

CloneNo. 93

宿主/亚型

Rat / IgG2a, lambda

种属反应性

mouse

应用

FC

CD16/32, CD32, 93, Fc gamma receptor IIB, Fc-gamma RII

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存


65057-1-Ig

产品信息

65057-1-PBS targets CD16/CD32 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 VH81X Tg B cells and T220 stromal cell line 种属同源性预测
宿主/亚型 Rat / IgG2a, lambda
抗体类别 Monoclonal
产品类型 Antibody
全称 Fc receptor, IgG, low affinity IIb
别名 CD16/32, CD32, 93, Fc gamma receptor IIB, Fc-gamma RII
GenBank蛋白编号BC038070
基因名称 CD16/32
Gene ID (NCBI) 14130
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP08101
储存缓冲液 PBS Only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD16 (FcγRIII) is a 50-70 kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD32 (FcγRII) is a 40 kD transmembrane glycoprotein that binds to the Fc region of IgG with low affinity. CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Rat anti mouse CD16/32 antibody, clone 93 is specific to the common epitope of CD16 and CD32. It can be used for blocking non-specific binding of immunoglobulins to the Fc receptors by preincubating the cells with the purified antibody at 1 ug per million cells in 100 uL volume for 5-10 minutes prior to immunostaining.

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