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验证数据展示

  • FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

    FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD147 Rabbit RecAb (98229-1-RR, Clone: 241852B4) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98229-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

    FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD147 Rabbit RecAb (98229-1-RR, Clone: 241852B4) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98229-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98229-1-RR

    Affinity and Kinetic Characterization of 98229-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98229-1-RR against Mouse CD147 were performed. The affinity constant is below 1 pM.

Anti-Mouse CD147 Rabbit Recombinant Antibody, PBS Only

CD147 Uni-rAb® Recombinant Antibody for FC
Cat No. 98229-1-PBS

产品说明书

CloneNo. 241852B4

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

241852B4, Basic immunoglobulin superfamily, Basigin, Bsg, HT7 antigen

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98229-1-PBS targets CD147 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原

CatNo: Eg1530

Product name: Recombinant Mouse CD147 protein (rFc Tag)

Source: mammalian cells-derived, pHZ-KIsec-C-rFc

Tag: C-rFc

Domain: 22-325 aa of NM_009768.2

Sequence: AAGFLKAPLSQERWAGGSVVLHCEAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLSVDGLTAEDTGTYECRASSDPDRNHLTRPPRVKWVRAQASVVVLEPGTIQTSVQEVNSKTQLTCSLNSSGVDIVGHRWMRGGKVLQEDTLPDLHTKYIVDADDRSGEYSCIFLPEPVGRSEINVEGPPRIKVGKKSEHSSEGELAKLVCKSDASYPPITDWFWFKTSDTGEEEAITNSTEANGKYVVVSTPEKSQLTISNLDVNVDPGTYVCNATNAQGTTRETISLRVRSR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 basigin
别名 241852B4, Basic immunoglobulin superfamily, Basigin, Bsg, HT7 antigen
计算分子量42 kDa
GenBank蛋白编号NM_009768.2
基因名称 CD147
Gene ID (NCBI) 12215
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP18572-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD147, also known as Basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 7812975). The molecule is composed of an intracellular portion, an extracellular portion and a single transmembrane region. CD147 is expressed on a variety of cell types (e.g., hematopoietic, epithelial, and endothelial cells) and at varying levels (PMID: 32968061). CD147 is a pleiotropic molecule that plays an important role in fetal, neuronal, lymphocyte and extracellular matrix development (PMID: 17945211).

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