×
Use Able AI chat for product recommendations

验证数据展示

  • FC experiment of human PBMCs using 98785-2-RR (same clone as 98785-2-PBS)

    FC experiment of human PBMCs using 98785-2-RR (same clone as 98785-2-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ITAM Rabbit RecAb (98785-2-RR, Clone:252751B5) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 405 Anti-Human CD14 Rabbit Recombinant Antibody (CL405-98040, Clone: 230332D7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98785-2-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98785-2-RR (same clone as 98785-2-PBS)

    FC experiment of human PBMCs using 98785-2-RR (same clone as 98785-2-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ITAM Rabbit RecAb (98785-2-RR, Clone:252751B5) (red) and PE-Conjugated Goat Anti-Rabbit IgG(H+L), and 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98785-2-PBS in a different storage buffer formulation.

Anti-Human CD11b Rabbit Recombinant Antibody, PBS Only

CD11b Uni-rAb® Recombinant Antibody for FC
Cat No. 98785-2-PBS

产品说明书

CloneNo. 252751B5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CD11 antigen-like family member B, Cell surface glycoprotein MAC-1 subunit alpha, CR 3 alpha chain, CR-3 alpha chain, CR3A

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy CD11B Ready-To-Use IHC Kit. CD11B primary antibody included.

产品信息

98785-2-PBS targets CD11b in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg10485

Product name: Recombinant human ITAM protein

Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

Tag: C-Twin-Strep-Tag

Domain: 10011430 of

Sequence: \

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 integrin, alpha M (complement component 3 receptor 3 subunit)
别名 CD11 antigen-like family member B, Cell surface glycoprotein MAC-1 subunit alpha, CR 3 alpha chain, CR-3 alpha chain, CR3A
基因名称 CD11b
Gene ID (NCBI) 3684
ENSEMBL Gene IDENSG00000169896
RRIDAB_3746346
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

||
New chat

Able™

正在加载，请稍候...