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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • FC experiment of rat bone marrow cells using 65606-1-MR (same clone as 65606-1-PBS)

    FC experiment of rat bone marrow cells using 65606-1-MR (same clone as 65606-1-PBS)

    1x10^6 rat bone marrow cells were surface stained with 0.25 ug Anti-Rat CD11b/c Mouse IgG2a Recombinant Antibody (65606-1-MR, Clone: OX42) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) and FITC anti-Mouse IgG2a Antibody. Cells were not fixed. This data was developed using the same antibody clone with 65606-1-PBS in a different storage buffer formulation.

  • FC experiment of rat bone marrow cells using 65606-1-MR (same clone as 65606-1-PBS)

    FC experiment of rat bone marrow cells using 65606-1-MR (same clone as 65606-1-PBS)

    1x10^6 rat bone marrow cells were surface stained with 0.25 ug Anti-Rat CD11b/c Mouse IgG2a Recombinant Antibody (65606-1-MR, Clone: OX42) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and FITC anti-Mouse IgG2a Antibody. Cells were not fixed. This data was developed using the same antibody clone with 65606-1-PBS in a different storage buffer formulation.

Anti-Rat CD11b/c (OX42) Mouse IgG2a Recombinant Antibody, PBS Only

CD11b/c Uni-rAb® Recombinant Antibody for FC
Cat No. 65606-1-PBS

产品说明书

CloneNo. OX42

宿主/亚型

Mouse / IgG2a

种属反应性

rat

应用

FC

别名

CD11b, integrin alpha M, Itgam, OX42

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

65606-1-PBS targets CD11b/c in FC applications and shows reactivity with rat samples.

经测试应用 FC Application Description
经测试反应性 rat
免疫原

fusion protein

种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 integrin alpha M
别名 CD11b, integrin alpha M, Itgam, OX42
计算分子量127 kDa
GenBank蛋白编号NM_012711
基因名称 CD11b
Gene ID (NCBI) 25021
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9JI30
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b (integrin alpha M or CR3A) and CD11c (integrin alpha X) are members of the integrin alpha chain family and can form α/β heterodimers with CD18 (integrin β2). CD11b/CD18 is a receptor for the complement protein fragment C3bi, and is also a receptor for fibrinogen, factor X, and ICAM1 (PMID: 2971974; 15485828). CD11c/CD18 acts as a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). The OX-42 antibody recognizes a common epitope shared between CD11b and CD11c. It binds to C3bi receptor and is known to block C3bi binding (PMID: 3512425; 8449218).