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验证数据展示

  • WB analysis of Jurkat using 60179-1-Ig (same clone as 60179-1-PBS)

    WB analysis of Jurkat using 60179-1-Ig (same clone as 60179-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 60179-1-Ig (CD109 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60179-1-PBS in a different storage buffer formulation.

CD109 Monoclonal antibody, PBS Only

CD109 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 60179-1-PBS

产品说明书

CloneNo. 2H8G7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, Indirect ELISA

别名

CD109, CD109 antigen, CD109 molecule, CPAMD7, p180, Platelet specific Gov antigen, r150, RP11 525G3.1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60179-1-PBS targets CD109 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 CD109 molecule
别名 CD109, CD109 antigen, CD109 molecule, CPAMD7, p180, Platelet specific Gov antigen, r150, RP11 525G3.1
计算分子量 162 kDa
观测分子量 162 kDa
GenBank蛋白编号BC152996
基因名称 CD109
Gene ID (NCBI) 135228
RRIDAB_10892668
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ6YHK3
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor.CD109 is a glycosyl-phosphatidylinositol-anchored glycoprotein that is a member of the a2-macroglobulin/C3, C4, C5 family of thioester-containing proteins. There're 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form. The antibody can recognize all these 4 isoforms.