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验证数据展示

  • FC experiment of human monocyte-derived mature dendritic cells using 98280-1-RR (same clone as 98280-1-PBS)

    FC experiment of human monocyte-derived mature dendritic cells using 98280-1-RR (same clone as 98280-1-PBS)

    1x10^6 human monocyte-derived mature dendritic cells were intracellularly stained with 0.25 ug Anti-Human CCL22 Rabbit RecAb (98280-1-RR, Clone: 241668D5) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98280-1-PBS in a different storage buffer formulation.

Anti-Human CCL22/MDC Rabbit Recombinant Antibody, PBS Only

CCL22/MDC Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98280-1-PBS

产品说明书

CloneNo. 241668D5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC (Intra)

别名

CCL22, MDC, ccl 22, C-C motif chemokine 22, CC chemokine STCP-1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98280-1-PBS targets CCL22/MDC in FC (Intra) applications and shows reactivity with human samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-C motif) ligand 22
别名 CCL22, MDC, ccl 22, C-C motif chemokine 22, CC chemokine STCP-1
计算分子量 93 aa, 11 kDa
GenBank蛋白编号BC027952
基因名称 CCL22/MDC
Gene ID (NCBI) 6367
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO00626
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The C-C motif chemokine ligand 22 (CCL22), also known as MDC, belongs to the group of chemokines, that are both constitutively expressed under homeostatic conditions and inducible upon inflammation. CCL22 is a secreted protein that exerts chemotactic activity for monocytes, dendritic cells, natural killer cells, and for chronically activated T lymphocytes. CCL22 is induced by LPS, IL-4, and IL-13 and in T cells by TCR stimulation. Accumulating studies indicate that CCL22 recruits regulatory T (T-reg) cells into tumor tissues and is expressed in many human tumors.