验证数据展示
产品信息
26333-1-PBS targets CCDC66 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag23421 Product name: Recombinant human CCDC66 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-364 aa of BC132827 Sequence: MTFSSTKDLCKQCIDKDCLHIQKEISPATPNMQKTRNTVNTSLVGKQKPHKKHITAENMKSSLVCLTQDQLQQILMTVNQGNRSLSLTENGKEAKSQYSLYLNSISNQPKDENIMGLFKKTEMVSSVPAENKSVLNEHQETSKQCEQKIAIENEWKPADIFSTLGERECDRSSLEAKKAQWRKELDEQVALKKKEKEVSEKWNDPWKKSESDKIIWEKHQILDQSRETVLLEHPFSAVKQELQRKWIEELNKQIEDDRQRKIEEKIIYSKGEEHDRWAMHFDSLKSYPGSQSQLFSRSTHKQPEYFCVSPDTQELADVSSVCTPTTGSQVEPSEEEHIAKPIKDVVMANSKKTNFLRSMTALLD 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | coiled-coil domain containing 66 |
| 别名 | Coiled-coil domain-containing protein 66 |
| 观测分子量 | 105-125 kDa |
| GenBank蛋白编号 | BC132827 |
| 基因名称 | CCDC66 |
| Gene ID (NCBI) | 285331 |
| RRID | AB_3742183 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | A2RUB6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CCDC66 is a MAP that localizes to the centriolar satellites, the centrosome and the primary cilium and is linked in ciliopathies affecting retina and brain. It interacts with the ciliopathy proteins CEP104 and CSPP1 and controls axonemal elongation (PMID: 36606424). CCDC66 is required for the basal body recruitment of transition zone proteins and intraflagellar transport B (IFT-B) machinery.
