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验证数据展示

  • IHC staining of mouse skin using 30688-1-AP (same clone as 30688-1-PBS)

    IHC staining of mouse skin using 30688-1-AP (same clone as 30688-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30688-1-AP (CCDC23 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30688-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse skin using 30688-1-AP (same clone as 30688-1-PBS)

    IHC staining of mouse skin using 30688-1-AP (same clone as 30688-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30688-1-AP (CCDC23 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30688-1-PBS in a different storage buffer formulation.

CCDC23 Polyclonal antibody, PBS Only

CCDC23 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 30688-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

SVBP, Coiled coil domain-containing protein 23, Small vasohibin-binding protein

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

30688-1-PBS targets CCDC23 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag33650

Product name: Recombinant human CCDC23 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-66 aa of BC029427

Sequence: MDPPARKEKTKVKESVSRVEKAKQKSAQQELKQRQRAEIYALNRVMTELEQQQFDEFCKQMQPPGE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 coiled-coil domain containing 23
别名 SVBP, Coiled coil domain-containing protein 23, Small vasohibin-binding protein
GenBank蛋白编号BC029427
基因名称 CCDC23
Gene ID (NCBI) 374969
RRIDAB_3742367
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8N300
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CCDC23 also known as SVBP is a small vasohibin-binding protein of 66 amino acids, and functions as a chaperone of VASH1 in vascular endothelial cells(PMID: 20736312). SVBP enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin(PMID: 29146869, 31171830). Mutations in SVBP cause Neurodevelopmental disorders with ataxia, hypotonia, and microcephaly (NEDAHM)(PMID: 30607023, 31363758).

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