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验证数据展示

  • IHC staining of mouse skin using 30688-1-AP

    IHC staining of mouse skin using 30688-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30688-1-AP (CCDC23 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse skin using 30688-1-AP

    IHC staining of mouse skin using 30688-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30688-1-AP (CCDC23 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CCDC23 Polyclonal antibody

CCDC23 Polyclonal Antibody for IHC, ELISA
Cat No. 30688-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, ELISA

别名

SVBP, Coiled coil domain-containing protein 23, Small vasohibin-binding protein

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inmouse skin tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

30688-1-AP targets CCDC23 in IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 CCDC23 fusion protein Ag33650 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 coiled-coil domain containing 23
别名 SVBP, Coiled coil domain-containing protein 23, Small vasohibin-binding protein
GenBank蛋白编号BC029427
基因名称 CCDC23
Gene ID (NCBI) 374969
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8N300
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CCDC23 also known as SVBP is a small vasohibin-binding protein of 66 amino acids, and functions as a chaperone of VASH1 in vascular endothelial cells(PMID: 20736312). SVBP enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin(PMID: 29146869, 31171830). Mutations in SVBP cause Neurodevelopmental disorders with ataxia, hypotonia, and microcephaly (NEDAHM)(PMID: 30607023, 31363758).

实验方案

Product Specific Protocols
IHC protocol for CCDC23 antibody 30688-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols