验证数据展示
产品信息
32228-1-PBS targets CCDC157 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag37002 Product name: Recombinant human CCDC157 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 223-491 aa of BC092419 Sequence: RWAAEQRKDLTRLSKHVEALRAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAEEDEQCLSEWEHDKQQLLTETSDLKTKMATLERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQLQSEREQGQCQLRAQQELLQSLQREKQGLEQATTDLRLTILELERELEELKERERLL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | coiled-coil domain containing 157 |
| 别名 | KIAA1656, Coiled-coil domain-containing protein 157 |
| 计算分子量 | 84 kDa, 752 aa |
| 观测分子量 | 85 kDa |
| GenBank蛋白编号 | BC092419 |
| 基因名称 | CCDC157 |
| Gene ID (NCBI) | 550631 |
| RRID | AB_3670225 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q569K6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CCDC157 is a member of the coiled‐coil domain‐containing (CCDC) family proteins, wich have a conserved coiled‐coil motif that is responsible for molecular recognition and protein refolding. CCDC157 is highly expressed in the testes from Drosophila to mammals. Bioinformatics database analysis suggests that CCDC157 expression is significantly decreased in NOA patients (PMID: 30741974). An in vitro study has reported that CCDC157 is localized on Golgi membranes along the secretory pathway and interacts with resident proteins of ER‐Golgi membranes (PMID: 31488582).
