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验证数据展示

  • WB analysis using 14534-1-AP (same clone as 14534-1-PBS)

    WB analysis using 14534-1-AP (same clone as 14534-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14534-1-AP (CASZ1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14534-1-PBS in a different storage buffer formulation.

  • IP experiment of C2C12 using 14534-1-AP (same clone as 14534-1-PBS)

    IP experiment of C2C12 using 14534-1-AP (same clone as 14534-1-PBS)

    IP result of anti-CASZ1 (IP:14534-1-AP, 4ug; Detection:14534-1-AP 1:1000) with C2C12 cells lysate 1200 ug. This data was developed using the same antibody clone with 14534-1-PBS in a different storage buffer formulation.

  • IP experiment of HUVEC using 14534-1-AP (same clone as 14534-1-PBS)

    IP experiment of HUVEC using 14534-1-AP (same clone as 14534-1-PBS)

    IP result of anti-CASZ1 (IP:14534-1-AP, 4ug; Detection:14534-1-AP 1:1000) with HUVEC cells lysate 1080 ug. This data was developed using the same antibody clone with 14534-1-PBS in a different storage buffer formulation.

CASZ1 Polyclonal antibody, PBS Only

CASZ1 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 14534-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, Indirect ELISA

别名

CAS11, Castor-related protein, CST, Putative survival-related protein, SRG

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

14534-1-PBS targets CASZ1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag6035

Product name: Recombinant human CASZ1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 818-1166 aa of BC051883

Sequence: PSLLGAVSSGSAASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGAPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWKVYLRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSSLEGPAPSPASVPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLENAKPQVKPGFLQFQEK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 castor zinc finger 1
别名 CAS11, Castor-related protein, CST, Putative survival-related protein, SRG
计算分子量 190 kDa
观测分子量150 kDa, 250 kDa
GenBank蛋白编号BC051883
基因名称 CASZ1
Gene ID (NCBI) 54897
RRIDAB_3669188
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86V15
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Zinc finger protein castor homolog 1 (CASZ1), also known as zinc finger protein 693 (ZNF693), belongs to the C2H2-type zinc finger protein family. CASZ1 is a transcription factor that is evolutionarily conserved and participates in multiple embryonic development and physiological processes. CASZ1 has been found to regulate aldosterone synthesis and repress the activation of aldosterone target genes, suggesting that it may participate in blood pressure regulation. CASZ1 is ubiquitously expressed in various embryonic tissues. Subcellularly, CASZ1 is usually localized in the cell nucleus, consistent with its role in transcription regulation (PMID: 37509718). CASZ1 has two isoforms namely CASZ1a (i.e., hcasz11, 190 kDa) and CASZ1b (i.e., hcasz5, 125 kDa). The observed molecular weights were 150 kDa and 250 kDa, respectively, consistent with descriptions in the literature (PMID: 32060262).

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