验证数据展示
产品信息
28373-1-PBS targets CARD14 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag28969 Product name: Recombinant human CARD14 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 280-566 aa of BC018142 Sequence: SLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQKSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSSTESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYELLDTADLPQLESSLQPVSPGRLDVSESGVLMRRRPARRIL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | caspase recruitment domain family, member 14 |
| 别名 | |
| 计算分子量 | 113 kDa |
| 观测分子量 | 110-140 kDa |
| GenBank蛋白编号 | BC018142 |
| 基因名称 | CARD14 |
| Gene ID (NCBI) | 79092 |
| RRID | AB_3669656 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9BXL6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CARD14, also known as CARMA2, is closely related to CARD9, CARD10 , and CARD11 , which upon activation, each form an oligomeric CBM signaling complex with B‐cell lymphoma 10 (BCL10) and mucosa‐associated lymphoid tissue lymphoma translocation protein 1 (MALT1). It is predominantly expressed in epithelial cells of esophagus, skin, and mucosal tissues, although some isoforms were also shown to be expressed in hematopoietic cell lines.(PMID: 36009554, PMID: 32343482)
