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验证数据展示

  • WB analysis using 18816-1-AP

    WB analysis using 18816-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 18816-1-AP (CAMSAP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

CAMSAP1 Polyclonal antibody

CAMSAP1 Polyclonal Antibody for WB, ELISA
Cat No. 18816-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, ELISA

别名

PRO2405, Calmodulin-regulated spectrin-associated protein 1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inSH-SY5Y cells, mouse brain tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

18816-1-AP targets CAMSAP1 in WB, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 calmodulin regulated spectrin-associated protein 1
别名 PRO2405, Calmodulin-regulated spectrin-associated protein 1
计算分子量 179 kDa
观测分子量245 kDa
GenBank蛋白编号BC144082
基因名称 CAMSAP1
Gene ID (NCBI) 157922
RRIDAB_3669303
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ5T5Y3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CAMSAP1, or Calmodulin-regulated spectrin-associated protein 1, is a protein that plays a crucial role in the formation and maintenance of the minus end of non-centrosomal microtubules, which are essential for proper neuronal function and development. Research has shown that CAMSAP1 is vital for neuronal polarization, migration, and cortical lamination. CAMSAP1 has also been implicated in cancer prognosis. A study found that CAMSAP1 mutation can activate anti-tumor immunity, mediate tumor cell apoptosis, inhibit epithelial-mesenchymal transition (EMT), improve prognosis, and improve platinum drug sensitivity in small-cell lung cancer patients treated with platinum-based chemotherapy, suggesting that CAMSAP1 mutation may be a potential biomarker indicating platinum drug sensitivity and patient prognosis. The CAMSAP1 of the calculated MW is around 170 kDa, and the observed MW is 245 kDa (PMID: 32839317).

实验方案

Product Specific Protocols
WB protocol for CAMSAP1 antibody 18816-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols