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验证数据展示

  • WB analysis of LNCaP using 33971-1-AP (same clone as 33971-1-PBS)

    WB analysis of LNCaP using 33971-1-AP (same clone as 33971-1-PBS)

    WB result of C12orf43 antibody (33971-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-C12orf43 transfected LNCaP cells. This data was developed using the same antibody clone with 33971-1-PBS in a different storage buffer formulation.

  • WB analysis using 33971-1-AP (same clone as 33971-1-PBS)

    WB analysis using 33971-1-AP (same clone as 33971-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33971-1-AP (C12orf43 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33971-1-PBS in a different storage buffer formulation.

C12orf43 Polyclonal antibody, PBS Only

C12orf43 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 33971-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

Chromosome 12 Open Reading Frame 43, CUSTOS, Protein CUSTOS

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

33971-1-PBS targets C12orf43 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag40576

Product name: Recombinant human C12orf43 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 33-142 aa of BC014661

Sequence: AWGLEQRPHVAGKPRAGAANSQLSTSQPSLRHKVNEHEQDGNELQTTPEFRAHVAKKLGALLDSFITISEAAKEPAKAKVQKVALEDDGFRLFFTSVPGGREKEESPQPR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 12 open reading frame 43
别名 Chromosome 12 Open Reading Frame 43, CUSTOS, Protein CUSTOS
观测分子量37 kDa
GenBank蛋白编号BC014661
基因名称 C12orf43
Gene ID (NCBI) 64897
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ96C57
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

C12orf43 (also known as CUSTOS) is a nuclear-localized protein. It is predicted to be involved in the formation of the Spemann organizer, a key process in embryonic development, and acts as a negative regulator of the Wnt signaling pathway. Studies have shown that C12orf43 is differentially expressed in various tumors, and its high expression in liver cancer and lung cancer is significantly associated with poor patient prognosis, establishing it as an unfavorable prognostic marker. Additionally, C12orf43 has been found to be associated with neurodegenerative diseases, autoimmune disorders, and other conditions.

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