×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of LNCaP using 33971-1-AP

    WB analysis of LNCaP using 33971-1-AP

    WB result of C12orf43 antibody (33971-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-C12orf43 transfected LNCaP cells.

  • WB analysis using 33971-1-AP

    WB analysis using 33971-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 33971-1-AP (C12orf43 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • KD/KO Validated

C12orf43 Polyclonal antibody

C12orf43 Polyclonal Antibody for WB, ELISA
Cat No. 33971-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

Chromosome 12 Open Reading Frame 43, CUSTOS, Protein CUSTOS

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
偶联物:  Unconjugated
Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive WB detected inA549 cells, LNCaP cells, ACHN cells, Calu-1 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

33971-1-AP targets C12orf43 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag40576

Product name: Recombinant human C12orf43 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 33-142 aa of BC014661

Sequence: AWGLEQRPHVAGKPRAGAANSQLSTSQPSLRHKVNEHEQDGNELQTTPEFRAHVAKKLGALLDSFITISEAAKEPAKAKVQKVALEDDGFRLFFTSVPGGREKEESPQPR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 12 open reading frame 43
别名 Chromosome 12 Open Reading Frame 43, CUSTOS, Protein CUSTOS
观测分子量37 kDa
GenBank蛋白编号BC014661
基因名称 C12orf43
Gene ID (NCBI) 64897
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ96C57
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

C12orf43 (also known as CUSTOS) is a nuclear-localized protein. It is predicted to be involved in the formation of the Spemann organizer, a key process in embryonic development, and acts as a negative regulator of the Wnt signaling pathway. Studies have shown that C12orf43 is differentially expressed in various tumors, and its high expression in liver cancer and lung cancer is significantly associated with poor patient prognosis, establishing it as an unfavorable prognostic marker. Additionally, C12orf43 has been found to be associated with neurodegenerative diseases, autoimmune disorders, and other conditions.

实验方案

Product Specific Protocols
WB protocol for C12orf43 antibody 33971-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
||
New chat

Able™

正在加载，请稍候...