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验证数据展示

  • IP experiment of SH-SY5Y using 26026-1-AP (same clone as 26026-1-PBS)

    IP experiment of SH-SY5Y using 26026-1-AP (same clone as 26026-1-PBS)

    IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with SH-SY5Y cells lysate 1920 ug. This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

  • IP experiment of HEK-293 using 26026-1-AP (same clone as 26026-1-PBS)

    IP experiment of HEK-293 using 26026-1-AP (same clone as 26026-1-PBS)

    IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with HEK-293 cells lysate 1600 ug. This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

  • IHC staining of rat pancreas using 26026-1-AP (same clone as 26026-1-PBS)

    IHC staining of rat pancreas using 26026-1-AP (same clone as 26026-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 26026-1-AP (C10orf88 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 26026-1-AP (same clone as 26026-1-PBS)

    IF Staining of A549 using 26026-1-AP (same clone as 26026-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using C10orf88 antibody (26026-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

C10orf88 Polyclonal antibody, PBS Only

C10orf88 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA
Cat No. 26026-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, rat

应用

IHC, IF/ICC, IP, Indirect ELISA

别名

ATPase PAAT, EC:3.6.1.-, PAAT, Protein associated with ABC transporters

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

26026-1-PBS targets C10orf88 in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, rat samples.

经测试应用 IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原

CatNo: Ag22971

Product name: Recombinant human C10orf88 protein

Source: e coli.-derived, PET30a

Tag: 6*His

Domain: 1-445 aa of BC032645

Sequence: METRTEDGGLTRRPTLASSWDVAGGALTHSLLLTRAGLGPGDFDWEELLAPPAPGQDLVILKRNHNNKDENPCFLYLRCGPDGGEEIASIGILSSARNMEVYLGEEYCGTSRGKNVCTVLDDSEHEKIILYKKNLKLESSTHACKIKLLSFGERQCVFISKVVVHMRSVFANSSTSSPALGSRIDLDKVQTIMESMGSKLSPGAQQLMDMVRCQQRNCIPIGEQLQSVLGNSGYKHMIGLQSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQNPNSPPTGIPLRHYDSGERLSNGER

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 10 open reading frame 88
别名 ATPase PAAT, EC:3.6.1.-, PAAT, Protein associated with ABC transporters
计算分子量 445 aa, 49 kDa
观测分子量49 kDa
GenBank蛋白编号BC032645
基因名称 C10orf88
Gene ID (NCBI) 80007
RRIDAB_3742165
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H8K7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

C10orf88 (Chromosome 10 Open Reading Frame 88) is a mitochondria-localized protein that is thought to be associated with protein-binding activity of mitochondria and plays a role in mitochondrial dysfunction and metabolic diseases. Studies suggest that C10orf88 may be involved in cellular metabolism, cell cycle regulation, and maintenance of mitochondrial homeostasis. Its activity is closely related to ATP synthesis and oxidative phosphorylation in mitochondria, and may be affected by a variety of metabolic regulators (e.g., metformin, AICAR) and cell cycle regulators (e.g., rosavitine). In addition, inhibitors of C10orf88 (e.g., oryzanamycin, rotenone) modulate its activity by affecting ATP synthase and electron transport chain complex I in mitochondria.

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