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验证数据展示

  • IP experiment of SH-SY5Y using 26026-1-AP

    IP experiment of SH-SY5Y using 26026-1-AP

    IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with SH-SY5Y cells lysate 1920 ug.

  • IP experiment of HEK-293 using 26026-1-AP

    IP experiment of HEK-293 using 26026-1-AP

    IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with HEK-293 cells lysate 1600 ug.

  • IF Staining of A549 using 26026-1-AP

    IF Staining of A549 using 26026-1-AP

    Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using C10orf88 antibody (26026-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2).

C10orf88 Polyclonal antibody

C10orf88 Polyclonal Antibody for IF/ICC, IP, ELISA
Cat No. 26026-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC, IP, ELISA

别名

ATPase PAAT, EC:3.6.1.-, PAAT, Protein associated with ABC transporters

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive IP detected inHEK-293 cells, SH-SY5Y cells
Positive IF/ICC detected inA549 cells

推荐稀释比

应用推荐稀释比
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26026-1-AP targets C10orf88 in IF/ICC, IP, ELISA applications and shows reactivity with human samples.

经测试应用 IF/ICC, IP, ELISA Application Description
经测试反应性 human
免疫原 C10orf88 fusion protein Ag22971 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 chromosome 10 open reading frame 88
别名 ATPase PAAT, EC:3.6.1.-, PAAT, Protein associated with ABC transporters
计算分子量 445 aa, 49 kDa
观测分子量49 kDa
GenBank蛋白编号BC032645
基因名称 C10orf88
Gene ID (NCBI) 80007
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H8K7
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

C10orf88 (Chromosome 10 Open Reading Frame 88) is a mitochondria-localized protein that is thought to be associated with protein-binding activity of mitochondria and plays a role in mitochondrial dysfunction and metabolic diseases. Studies suggest that C10orf88 may be involved in cellular metabolism, cell cycle regulation, and maintenance of mitochondrial homeostasis. Its activity is closely related to ATP synthesis and oxidative phosphorylation in mitochondria, and may be affected by a variety of metabolic regulators (e.g., metformin, AICAR) and cell cycle regulators (e.g., rosavitine). In addition, inhibitors of C10orf88 (e.g., oryzanamycin, rotenone) modulate its activity by affecting ATP synthase and electron transport chain complex I in mitochondria.

实验方案

Product Specific Protocols
IF protocol for C10orf88 antibody 26026-1-APDownload protocol
IP protocol for C10orf88 antibody 26026-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols