×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 33133-1-AP (same clone as 33133-1-PBS)

    WB analysis using 33133-1-AP (same clone as 33133-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33133-1-AP (BXDC5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33133-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 33133-1-AP (same clone as 33133-1-PBS)

    IF Staining of U2OS using 33133-1-AP (same clone as 33133-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using BXDC5 antibody (33133-1-AP) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 33133-1-PBS in a different storage buffer formulation.

BXDC5 Polyclonal antibody, PBS Only

BXDC5 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 33133-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

Brix domain-containing protein 5, Ribosome biogenesis protein RPF1, Ribosome production factor 1, Ribosome Production Factor 1 Homolog, RPF1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

33133-1-PBS targets BXDC5 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag37505

Product name: Recombinant human BXDC5 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-349 aa of BC016051

Sequence: MAKAGDKSGSSGKKSLKRKAAAEELQEAAGAGDGATENGVQPPKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 brix domain containing 5
别名 Brix domain-containing protein 5, Ribosome biogenesis protein RPF1, Ribosome production factor 1, Ribosome Production Factor 1 Homolog, RPF1
计算分子量 349 aa, 40 kDa
观测分子量48 kDa
GenBank蛋白编号BC016051
基因名称 BXDC5
Gene ID (NCBI) 80135
RRIDAB_3742865
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ9H9Y2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BXDC5 (Brix domain-containing protein 5), also known as ribosome biogenesis protein RPF1, is a protein containing a Brix domain and is localized in the nucleolus. The Brix domain is a region that shares homology with the yeast protein Pitx1 (ribosome biogenesis protein BRX1). BXDC5 is a key factor in ribosome biogenesis, participating in the maturation of the 60S ribosomal subunit. This protein exerts its function by binding to specific rRNA structures and acts as a downstream effector molecule of the Ran signaling pathway, involved in ribosome biogenesis. In colorectal cancer (CRC), BXDC5 influences the occurrence and development of tumors by regulating ribosome biogenesis.

||
New chat

Able™

正在加载，请稍候...