×
Use Able AI chat for product recommendations

BRCA1-IN-2

BRCA1-IN-2 是一种可穿过细胞膜的 BRCA1 蛋白-蛋白相互作用（PPI）抑制剂，具有抗肿瘤活性，通过破坏 BRCA1 (BRCT)2 与蛋白质的相互作用来发挥作用。

CAS号

1622262-55-8

分子式

C26H33N4O7P

主要靶点

PARP|Others

仅限科研使用

Cat No : CM21125

Print datasheet

Synonyms

protein–protein interaction (PPI)|BRCA1IN2|BRCA1 IN 2|BRCA-1-IN-2|BRCA1-IN-2|BRCA1

验证数据展示

  • CAS No.: 1622262-55-8

    BRCA1-IN-2
    CAS#: 1622262-55-8

产品信息

BRCA1-IN-2 is a cell membrane-crossing BRCA1 protein-protein interaction (PPI) inhibitor with antitumor activity that acts by disrupting the interaction of BRCA1 (BRCT)2 with proteins.

CAS号 1622262-55-8
分子式 C26H33N4O7P
主要靶点 PARP|Others
主要通路 其他
分子量 544.54
纯度 98.04%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
别名 protein–protein interaction (PPI)|BRCA1IN2|BRCA1 IN 2|BRCA-1-IN-2|BRCA1-IN-2|BRCA1

靶点活性

BRCA1:0.31 μM|BRCA1:0.3 μM (Kd)

溶解度

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.06 mM);DMSO:80 mg/mL (146.91 mM)

参考文献

1.Na Z, et al. Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. Methods Mol Biol. 2017;1518:139-156.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2
||
New chat

Able™

正在加载，请稍候...