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验证数据展示

  • IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

    IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

    IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

    IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

    IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 13299-1-AP (same clone as 13299-1-PBS)

    IF Staining of HepG2 using 13299-1-AP (same clone as 13299-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using BNP antibody (13299-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

BNP/NPPB Polyclonal antibody, PBS Only

BNP/NPPB Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 13299-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, Indirect ELISA

别名

Natriuretic peptides B, NPPB, BNP, BNP(1 32), BNP(1-28)

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13299-1-PBS targets BNP/NPPB in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag4039

Product name: Recombinant human BNP protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-134 aa of BC025785

Sequence: MDPQTAPSRALLLLLFLHLAFLGGRSHPLGSPGSASDLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESPRPTGVWKSREVATEGIRGHRKMVLYTLRAPRSPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 natriuretic peptide precursor B
别名 Natriuretic peptides B, NPPB, BNP, BNP(1 32), BNP(1-28)
计算分子量 134 aa, 15 kDa
GenBank蛋白编号BC025785
基因名称 BNP
Gene ID (NCBI) 4879
RRIDAB_2877935
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP16860
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.

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