×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 33050-1-AP (same clone as 33050-1-PBS)

    WB analysis using 33050-1-AP (same clone as 33050-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33050-1-AP (BBIP1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33050-1-PBS in a different storage buffer formulation.

  • WB analysis of U-87 MG using 33050-1-AP (same clone as 33050-1-PBS)

    WB analysis of U-87 MG using 33050-1-AP (same clone as 33050-1-PBS)

    WB result of BBIP1 antibody (33050-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-BBIP1 transfected U-87 MG cells. This data was developed using the same antibody clone with 33050-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

BBIP1 Polyclonal antibody, PBS Only

BBIP1 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 33050-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

BBIP10, BBSome Interacting Protein 1, BBSome-interacting protein 1, BBSome-interacting protein of 10 kDa, NCRNA00081

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

33050-1-PBS targets BBIP1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag36924

Product name: Recombinant human BBIP1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-92 aa of BC015550

Sequence: MLKAAAKRPELSGKNTISNNSDMAEVKSMFREVLPKQGPLFVEDIMTMVLCKPKLLPLKSLTLEKLEKMHQAAQNTIRQQEMAEKDQRQITH*

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 non-protein coding RNA 81
别名 BBIP10, BBSome Interacting Protein 1, BBSome-interacting protein 1, BBSome-interacting protein of 10 kDa, NCRNA00081
观测分子量22 kDa
GenBank蛋白编号BC015550
基因名称 NCRNA00081
Gene ID (NCBI) 92482
RRIDAB_3742837
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDA8MTZ0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The BBIP1 protein is a key component of the BBSome complex and was identified due to its role in the pathogenesis of Bardet-Biedl syndrome (BBS). This protein localizes to the base of cellular cilia and plays an indispensable role in ciliary assembly, maintenance, and signal transduction. As an adapter for membrane protein trafficking, BBIP1 works in coordination with other members of the BBSome to precisely transport specific cargo proteins into the cilium, an important cellular organelle. Loss of its function disrupts the stability of the BBSome complex, leading to abnormalities in ciliary structure and function. This, in turn, causes various clinical symptoms of BBS, including retinal degeneration, obesity, and polydactyly. Therefore, research on BBIP1 is central to understanding the molecular basis of cilia-related diseases (ciliopathies).

||
New chat

Able™

正在加载，请稍候...