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验证数据展示

  • WB analysis using 14880-1-AP (same clone as 14880-1-PBS)

    WB analysis using 14880-1-AP (same clone as 14880-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14880-1-AP (BASP1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14880-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 14880-1-AP (same clone as 14880-1-PBS)

    IHC staining of mouse brain using 14880-1-AP (same clone as 14880-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 14880-1-AP (BASP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14880-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BASP1 antibody included
  • IHC staining of human skin cancer using 14880-1-AP (same clone as 14880-1-PBS)

    IHC staining of human skin cancer using 14880-1-AP (same clone as 14880-1-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 14880-1-AP (BASP1 antibody) at dilution of 1:1600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14880-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BASP1 antibody included
  • IHC staining of human skin cancer using 14880-1-AP (same clone as 14880-1-PBS)

    IHC staining of human skin cancer using 14880-1-AP (same clone as 14880-1-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 14880-1-AP (BASP1 antibody) at dilution of 1:1600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14880-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BASP1 antibody included

BASP1 Polyclonal antibody, PBS Only

BASP1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 14880-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

22 kDa neuronal tissue-enriched acidic protein, Brain acid soluble protein 1, CAP 23, CAP23, NAP 22

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy BASP1 Ready-To-Use IHC Kit. BASP1 primary antibody included.

产品信息

14880-1-PBS targets BASP1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag6653

Product name: Recombinant human BASP1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-227 aa of BC000518

Sequence: MGGKLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTGAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEPKPVEAPAANSDQTVTVKE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 brain abundant, membrane attached signal protein 1
别名 22 kDa neuronal tissue-enriched acidic protein, Brain acid soluble protein 1, CAP 23, CAP23, NAP 22
计算分子量 23 kDa
观测分子量 55-60 kDa
GenBank蛋白编号BC000518
基因名称 BASP1
Gene ID (NCBI) 10409
RRIDAB_3085444
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP80723
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BASP1 (brain acid-soluble protein 1), also known as NAP22 or CAP-23, is an evolutionarily conserved intrinsically disordered protein that participates in cell signaling, migration, apoptosis, and gene transcription. It is highly expressed in the nervous system and plays roles in neurodevelopment, synaptic function, and nerve regeneration. BASP1 exhibits context-dependent functions in disease: it acts as a tumor suppressor in gastric cancer by inhibiting the Wnt/β-catenin pathway and in acute myeloid leukemia, while promoting atherosclerosis via vascular smooth muscle cell proliferation and inflammation. It has emerged as a promising therapeutic target and diagnostic biomarker. (PMID: 33426068; 41415108; 33015061)

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