Alpha Synuclein Monoclonal antibody, PBS Only (Detector)
Alpha Synuclein Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, rat, mouse
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
1B10E9
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy Alpha Synuclein Ready-To-Use IHC Kit. Alpha Synuclein primary antibody included.
产品信息
66412-1-PBS targets Alpha Synuclein as part of a matched antibody pair:
MP50043-1: 60285-1-PBS capture and 66412-1-PBS detection (validated in Sandwich ELISA)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Applications | ELISA |
| Tested Reactivity | human, rat, mouse |
| Immunogen | Alpha Synuclein fusion protein Ag1285 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | synuclein, alpha (non A4 component of amyloid precursor) |
| Synonyms | Alpha synuclein, NACP, PARK1, PARK4, PD1, SNCA |
| Calculated Molecular Weight | 14 kDa |
| Observed Molecular Weight | 18-19 kDa |
| GenBank Accession Number | BC013293 |
| Gene Symbol | SNCA |
| Gene ID (NCBI) | 6622 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P37840 |
| Storage Buffer | PBS only |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Alpha Synuclein (α-syn) is a 14-19 kDa phosphoprotein that is primarily localize to the presynaptic terminals of mature neurons, where it is involved in synaptic function and plasticity. α-syn has drawn intense interest ever since the late 1990s, when the first α-synuclein missense mutation was identified as a cause of familial Parkinson's disease (PD). Aggregated and hyper-phosphorylated forms of α-syn protein are the pathological hallmark of Lewy body disease, which includes Parkinson's disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer's disease (LBV). This antibody can recognize all the isoforms of α-syn.