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验证数据展示

  • WB analysis using 27691-1-AP (same clone as 27691-1-PBS)

    WB analysis using 27691-1-AP (same clone as 27691-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27691-1-AP (AVPR2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27691-1-PBS in a different storage buffer formulation.

  • WB analysis using 27691-1-AP (same clone as 27691-1-PBS)

    WB analysis using 27691-1-AP (same clone as 27691-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27691-1-AP (AVPR2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27691-1-PBS in a different storage buffer formulation.

AVPR2 Polyclonal antibody, PBS Only

AVPR2 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 27691-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

ADHR, Antidiuretic hormone receptor, AVPR V2, DI1, DIR

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

27691-1-PBS targets AVPR2 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag24835

Product name: Recombinant human AVPR2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-83 aa of BC112181

Sequence: MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 arginine vasopressin receptor 2
别名 ADHR, Antidiuretic hormone receptor, AVPR V2, DI1, DIR
计算分子量 371 aa, 40 kDa
观测分子量49 kDa
GenBank蛋白编号BC112181
基因名称 AVPR2
Gene ID (NCBI) 554
RRIDAB_3742249
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP30518
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

AVPR2 is a Gs-coupled vasopressin receptor essential for renal water reabsorption, acting through cAMP-PKA-dependent trafficking of aquaporin-2. Localized to principal cells of the collecting duct, AVPR2 integrates hormonal cues to maintain osmotic and fluid homeostasis. Mutations lead to X-linked nephrogenic diabetes insipidus, while rare activating variants cause SIADH. Because of its central role in renal physiology and clear clinical associations, AVPR2 is a key target in water-balance disorders and pharmacologic modulation of diuresis.

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