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验证数据展示

  • IF Staining of HepG2 using 17528-1-AP (same clone as 17528-1-PBS)

    IF Staining of HepG2 using 17528-1-AP (same clone as 17528-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using AURKAIP1 antibody (17528-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-phalloidin (red). This data was developed using the same antibody clone with 17528-1-PBS in a different storage buffer formulation.

AURKAIP1 Polyclonal antibody, PBS Only

AURKAIP1 Polyclonal Antibody for IF/ICC, Indirect ELISA
Cat No. 17528-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC, Indirect ELISA

别名

28S ribosomal protein S38, mitochondrial, AIP, AKIP, AURKA interacting protein, AURKA-interacting protein

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

17528-1-PBS targets AURKAIP1 in applications and shows reactivity with human samples.

经测试应用 IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag11444

Product name: Recombinant human AURKAIP1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-199 aa of BC062333

Sequence: MLLGRLTSQLLRAVPWAGGRPPWPVSGVLGSRVCGPLYSTSPAGPGRAASLPRKGAQLELEEMLVPRKMSVSPLESWLTARCFLPRLDTGTAGTVAPPQSYQCPPSQIGEGAEQGDEGVADAPQIQCKNVLKIRRRKMNHHKYRKLVKKTRFLRRKVQEGRLRRKQIKFEKDLRRIWLKAGLKEAPEGWQTPKIYLRGK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 aurora kinase A interacting protein 1
别名 28S ribosomal protein S38, mitochondrial, AIP, AKIP, AURKA interacting protein, AURKA-interacting protein
计算分子量 199 aa, 22 kDa
GenBank蛋白编号BC062333
基因名称 AURKAIP1
Gene ID (NCBI) 54998
RRIDAB_3741922
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NWT8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

AURKAIP1 (Aurora-A kinase interacting protein 1) has been identified as an Aurora-A kinase interacting protein involving in two degradation pathways of Aurora-A, including proteasome-dependent pathway and Ub-independent pathway . Ectopic expression of AURKAIP1 resulted in the down-regulation of Aurora-A protein levels and thus, AURKAIP1 could be regarded as a cancer suppressor involving Aurora-A pathway.(PMID: 38040691,PMID: 17125467)

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