ARNTL Recombinant antibody

ARNTL Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 86113-1-RR

产品说明书

CloneNo. 250536E10

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

BMAL1, ARNT3, Aryl hydrocarbon receptor nuclear translocator-like protein 1, Basic helix-loop-helix ARNT-like protein 1, Basic-helix-loop-helix-PAS protein MOP3

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inHeLa cells, SH-SY5Y cells, HT-1080 cells, NIH/3T3 cells, mouse liver tissue, rat liver tissue
Planning an IHC experiment? We recommend our IHCeasy BMAL1/ARNTL Ready-To-Use IHC Kit. BMAL1/ARNTL primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

86113-1-RR targets ARNTL in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ARNTL fusion protein Ag5586 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 aryl hydrocarbon receptor nuclear translocator-like
别名 BMAL1, ARNT3, Aryl hydrocarbon receptor nuclear translocator-like protein 1, Basic helix-loop-helix ARNT-like protein 1, Basic-helix-loop-helix-PAS protein MOP3
计算分子量 69 kDa
观测分子量 69-75 kDa
GenBank蛋白编号BC041129
基因名称 ARNTL
Gene ID (NCBI) 406
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO00327
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BMAL1, a basic helix-loop-helices with Per-Arnt-Sim (PAS) domain transcription factor, is one of components that has core clock function in mammals. It form a heterodimer with CLOCK, and induce the transcription of target genes by binding to E-box elements within their promoter regions. And this transcription is inhibited in a feedback loop by PER, and also by CRY proteins.Also BMAL1 is a key player in the regulation of metabolism, playing a role in adipogenesis and in the control of glucose and triglycerides levels. Due to phosphorylation modification, BMAL1 can be detected as a band in the range of 70-80 kda (PMID: 14750952).

实验方案

Product Specific Protocols
WB protocol for ARNTL antibody 86113-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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