验证数据展示
经过测试的应用
| Positive WB detected in | VCaP cells |
Planning an IHC experiment? We recommend our IHCeasy AR Ready-To-Use IHC Kit. AR primary antibody included.
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
81847-2-RR targets AR-V7 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | androgen receptor |
| 别名 | androgen receptor, androgen receptor,AR, AR, DHTR, NR3C4 |
| 计算分子量 | 644aa, 67 kDa |
| 观测分子量 | 85 kDa |
| GenBank蛋白编号 | NM_001348061 |
| 基因名称 | AR |
| Gene ID (NCBI) | 367 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P10275 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Androgen Receptor Splice Variant 7 (AR-V7) is a truncated, constitutively active isoform of the human androgen receptor (AR). The presence of the AR-V7 protein is highly correlated with clinical resistance to next-generation androgen receptor signaling inhibitors (ARSIs), such as enzalutamide and abiraterone.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for AR-V7 antibody 81847-2-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
