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验证数据展示

  • FC experiment of human PBMCs using 98810-1-RR (same clone as 98810-1-PBS)

    FC experiment of human PBMCs using 98810-1-RR (same clone as 98810-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ANTXR2 Rabbit RecAb (98810-1-RR, Clone: 252595F1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD16. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98810-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98810-1-RR (same clone as 98810-1-PBS)

    FC experiment of human PBMCs using 98810-1-RR (same clone as 98810-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ANTXR2 Rabbit RecAb (98810-1-RR, Clone: 252595F1) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98810-1-PBS in a different storage buffer formulation.

  • Affinity of 98810-1-RR

    Affinity of 98810-1-RR

    Biolayer interferometry (BLI) kinetic assays of 98810-1-RR against Human ANTXR2 were performed. The affinity constant is below 1 pM.

Anti-Human ANTXR2 Rabbit Recombinant Antibody, PBS Only

ANTXR2 Uni-rAb® Recombinant Antibody for FC
Cat No. 98810-1-PBS

产品说明书

CloneNo. 252595F1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

Anthrax toxin receptor 2, CMG 2, CMG2, CMG-2, ISH

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy ANTXR2 Ready-To-Use IHC Kit. ANTXR2 primary antibody included.

产品信息

98810-1-PBS targets ANTXR2 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

CatNo: Eg7580

Product name: Recombinant Human ANTXR2 protein (rFc Tag)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 34-318 aa of NM_001145794

Sequence: QEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 anthrax toxin receptor 2
别名 Anthrax toxin receptor 2, CMG 2, CMG2, CMG-2, ISH
计算分子量54 kDa
GenBank蛋白编号NM_001145794
基因名称 ANTXR2
Gene ID (NCBI) 118429
RRIDAB_3746357
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP58335-1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ANTXR2 (anthrax toxin receptor 2), also known as CMG2 (capillary morphogenesis gene 2 protein) is a transmembrane protein that is induced during capillary morphogenesis. It contains a vWA domain that shows strong binding to laminin and collagen IV, suggesting that this protein plays a role in basement membrane matrix assembly and endothelial cell morphogenesis (PMID: 11683410; 14508707). Like its paralog TEM8 (ANTXR1), ANTXR2 also functions as a receptor for anthrax toxin. Mutations in ANTXR2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis (PMID: 14508707; 12973667; 22383261).

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