验证数据展示
产品信息
68719-1-PBS targets ALPL in WB, Indirect ELISA applications and shows reactivity with Human, pig, rabbit samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, pig, rabbit |
免疫原 | ALPL fusion protein Ag33678 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | alkaline phosphatase, liver/bone/kidney |
别名 | ALPL, AP TNAP, FLJ40094, FLJ93059, HOPS, TNAP, TNSALP |
计算分子量 | 57 kDa |
观测分子量 | 80 kDa |
GenBank蛋白编号 | BC021289 |
基因名称 | ALPL |
Gene ID (NCBI) | 249 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P05186 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. ALPL(Alkaline phosphatase, tissue-nonspecific isozyme) is also named as AP-TNAP, TNSALP and belongs to the alkaline phosphatase family. It can exsit as a homodimer with the molecular weight of 140 kDa(PMID:18724009). ALPL was synthesized as a 66-kDa endo-b-N-acetylglucos-aminidase H (Endo H)-sensitive form, and processed to an 80-kDa mature form, which is anchored to the plasma membrane via glycosylphosphatidylinositol (GPI)(PMID:10839996).