验证数据展示
产品信息
33485-1-PBS targets ALPI in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag36025 Product name: Recombinant human ALPI protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 20-220 aa of BC132678 Sequence: VIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILG 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | alkaline phosphatase, intestinal |
| 别名 | EC:3.1.3.1, IAP, Intestinal alkaline phosphatase, Intestinal-type alkaline phosphatase |
| 计算分子量 | 56 kDa |
| 观测分子量 | 55 kDa |
| GenBank蛋白编号 | BC132678 |
| 基因名称 | ALPI |
| Gene ID (NCBI) | 248 |
| RRID | AB_3742989 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | P09923 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ALPI (intestinal alkaline phosphatase) is a brush-border enzyme expressed in the gut that plays a critical role in maintaining intestinal homeostasis. By dephosphorylating pro-inflammatory microbial products, it helps prevent bacterial translocation and systemic inflammation. Dysfunction or deficiency of ALPI is linked to conditions such as increased intestinal permeability, metabolic disorders, and inflammatory diseases, making it a promising therapeutic target for preserving gut health.

