验证数据展示
产品信息
22649-1-PBS targets AKIRIN1 in IP, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IP, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag18530 Product name: Recombinant human AKIRIN1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-129 aa of BC119745 Sequence: MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPPDAEPPPPFQTQTPPQSLQQPAPPGSERRLPTPEQIFQNIKQEYSRYQRWRHLEVVLNQSEACASESQPHSSALTAPSSPGSSWMKKDQ 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | akirin 1 |
| 别名 | akirin 1, C1orf108, RP11 781D11.2, STRF2 |
| 计算分子量 | 192 aa, 22 kDa |
| 观测分子量 | 22 kDa |
| GenBank蛋白编号 | BC119745 |
| 基因名称 | AKIRIN1 |
| Gene ID (NCBI) | 79647 |
| RRID | AB_3742075 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H9L7 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Akirin1 is a highly conserved ubiquitously expressed nuclear protein harboring a clear nuclear localization signal and the protein-protein interaction property. Acting as a cofactor, Akirin1 has been disclosed that regulate transcriptional activities by establishing a link between multiple transcription factors and chromatin remodeling complexes (PMID: 39188701) . Akirin1 has been shown to be involved in the induction of cardiac hypertrophy via miR-1 and serum response factor (SRF) in mice (PMID: 30746755).
