CoraLite®594-conjugated AGR2 Monoclonal antibody
AGR2 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG2b
Reactivity
Human, Pig
Applications
IF/ICC
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1A8A8
验证数据展示
经过测试的应用
| Positive IF detected in | HT-29 cells |
Planning an IHC experiment? We recommend our IHCeasy AGR2 Ready-To-Use IHC Kit. AGR2 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 66768-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-66768 targets AGR2 in IF applications and shows reactivity with Human, Pig samples.
| Tested Applications | IF/ICC |
| Tested Reactivity | Human, Pig |
| Immunogen | AGR2 fusion protein Ag2919 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | anterior gradient homolog 2 (Xenopus laevis) |
| Synonyms | AG 2, AG2, AGR2, GOB 4, HAG 2, HPC8, PDIA17, XAG 2 |
| Calculated Molecular Weight | 175 aa, 20 kDa |
| Observed Molecular Weight | 17 kDa |
| GenBank Accession Number | BC015503 |
| Gene Symbol | AGR2 |
| Gene ID (NCBI) | 10551 |
| RRID | AB_2920033 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O95994 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. AGR2 was significantly elevated in the pancreatic juice from patients with pre-malignant conditions as well as pancreatic cancer compared to control pancreatic juice samples. AGR2 levels in pancreatic juice could potentially be used to aide in assessment of high-risk patients undergoing endoscopic procedures.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 AGR2 antibody CL594-66768 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |