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验证数据展示

  • WB analysis using 13847-1-AP (same clone as 13847-1-PBS)

    WB analysis using 13847-1-AP (same clone as 13847-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13847-1-AP (ACSL6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 13847-1-AP (same clone as 13847-1-PBS)

    IP experiment of mouse brain using 13847-1-AP (same clone as 13847-1-PBS)

    IP result of anti-ACSL6 (IP:13847-1-AP, 4ug; Detection:13847-1-AP 1:2000) with mouse brain tissue lysate 2120 ug. This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

  • IHC staining of human urothelial carcinoma using 13847-1-AP (same clone as 13847-1-PBS)

    IHC staining of human urothelial carcinoma using 13847-1-AP (same clone as 13847-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 13847-1-AP (ACSL6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 13847-1-AP (same clone as 13847-1-PBS)

    IHC staining of human pancreas cancer using 13847-1-AP (same clone as 13847-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 13847-1-AP (ACSL6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

ACSL6 Polyclonal antibody, PBS Only

ACSL6 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 13847-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

ACSL 6, Arachidonate--CoA ligase, EC:6.2.1.15, EC:6.2.1.3, FACL6

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13847-1-PBS targets ACSL6 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag4817

Product name: Recombinant human ACSL6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 48-349 aa of BC047453

Sequence: THYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQANHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 acyl-CoA synthetase long-chain family member 6
别名 ACSL 6, Arachidonate--CoA ligase, EC:6.2.1.15, EC:6.2.1.3, FACL6
计算分子量 78 kDa
观测分子量74 kDa
GenBank蛋白编号BC047453
基因名称 ACSL6
Gene ID (NCBI) 23305
RRIDAB_3741844
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UKU0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ACSL6 (Acyl-CoA Synthetase Long Chain Family Member 6) is a long-chain lipoyl-coenzyme A synthetase that is mainly responsible for catalyzing the binding of long-chain fatty acids to coenzyme A to form acyl-coenzyme A (Acyl-CoA). ACSL6 is involved in fatty acid metabolic transporter and the synthesis of cell membrane phospholipids, which affects the cell structure and function. ACSL6 plays an extremely important role in the pathogenesis of cancers such as hepatocellular carcinoma, lung cancer and neuroblastoma, suggesting that it may serve as a biomarker and therapeutic target for cancer therapy.

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