验证数据展示
产品信息
22660-1-PBS targets ABHD12 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag18522 Product name: Recombinant human ABHD12 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 88-404 aa of BC014049 Sequence: FLIKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQGLNHTCNYYLQPEEDVTIGVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCERETPPDALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQFVPFHSDLGYRHKYIYKSPELPRILRPQQGPGSSPDPSMWSELV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | abhydrolase domain containing 12 |
| 别名 | ABHD12A, BEM46L2, C20orf22 |
| 计算分子量 | 404 aa, 46 kDa |
| 观测分子量 | 42-45 kDa |
| GenBank蛋白编号 | BC014049 |
| 基因名称 | ABHD12 |
| Gene ID (NCBI) | 26090 |
| RRID | AB_3742076 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8N2K0 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ABHD12 is a recently identified post-genomic protein with poorly defined physiological function. Its potential role as a brain 2-AG hydrolase was revealed using ABPP with mouse brain proteome and it was estimated that at the bulk brain level. ABHD12 is a major brain lyso-PS lipase, implicating lyso-PSs in the neurological disease PHARC, which is caused by null mutations in the ABHD12 gene (PMID: 21418147, 25580854).
