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验证数据展示

  • WB analysis using 27722-1-AP (same clone as 27722-1-PBS)

    WB analysis using 27722-1-AP (same clone as 27722-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27722-1-AP (ABCG5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27722-1-PBS in a different storage buffer formulation.

  • WB analysis using 27722-1-AP (same clone as 27722-1-PBS)

    WB analysis using 27722-1-AP (same clone as 27722-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27722-1-AP (ABCG5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27722-1-PBS in a different storage buffer formulation.

  • WB analysis using 27722-1-AP (same clone as 27722-1-PBS)

    WB analysis using 27722-1-AP (same clone as 27722-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27722-1-AP (ABCG5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27722-1-PBS in a different storage buffer formulation.

ABCG5 Polyclonal antibody, PBS Only

ABCG5 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 27722-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

Sterolin 1, STSL

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

27722-1-PBS targets ABCG5 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag26844

Product name: Recombinant human ABCG5 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-85 aa of NM_022436

Sequence: MGDLSSLTPGGSMGLQVNRGSQSSLEGAPATAPEPHSLGILHASYSVSHRVRPWWDITSCRQQWTRQILKDVSLYVESGQIMCIL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ATP-binding cassette, sub-family G (WHITE), member 5
别名 Sterolin 1, STSL
计算分子量 72 kDa
观测分子量 68 kDa~72 kDa
GenBank蛋白编号NM_022436
基因名称 ABCG5
Gene ID (NCBI) 64240
RRIDAB_2880952
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H222
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ABCG5 belongs to the ABC transporter subfamily, whose members are "half-transporters" that require the formation of homodimers or heterodimers to function(PMID: 14504269). ABCG5 and ABCG8 form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of cholesterol and phytosterols(PMID: 24252657). Mutations in ABCG5e may contribute to sterol accumulation and atherosclerosis(PMID: 15054092).

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